Contact us -
Legal notice - Chinese reg.num.(京ICP备06015605号) - Last modified:
4-feb-11
- ©2004-11 Bio-Logic SAS -
|
|
|
| Note: this list is not supposed to cover all articles published by our clients.
Charged residues in the GABA-A receptor beta-2 subunit are crucial
for efficient receptor activation. Neural subtype specification of fertilization and nuclear transfer
embryonic stem cells and application in parkinsonian mice. The actions of sevoflurane and desflurane on the gamma-aminobutyric
acid receptor type A: effects of TM2 mutations in the alpha and beta
subunits. A highly conserved aspartic acid residue in the signature disulfide
loop of the alpha 1 subunit is a determinant of gating in the glycine
receptor. Hemoglobin metabolites mimic benzodiazepines and are possible
mediators of hepatic encephalopathy. Effects of isoflurane on gamma-aminobutyric acid type A receptors
activated by full and partial agonists. Coupling of agonist binding to channel gating in the GABA(A)
receptor. Molecular volume determines the activity of the halogenated alkane
bromoform at wild-type and mutant GABA(A) receptors. Kash TL, Jenkins A,
Harrison NL. Tryptophan scanning mutagenesis in TM4 of the GABA(A) receptor alpha1
subunit: implications for modulation by inhaled anesthetics and ion
channel structure. Volatile anesthetic actions on the GABAA receptors: contrasting
effects of alpha 1(S270) and beta 2(N265) point mutations. Methionine 286 in transmembrane domain 3 of the GABAA receptor beta
subunit controls a binding cavity for propofol and other alkylphenol
general anesthetics. Neuropharmacology. Expression of glycine receptors in rat sensory neurons vs. HEK293
cells yields different functional properties. Anesthetic properties of 4-iodopropofol: implications for mechanisms
of anesthesia. General anesthetic potencies of a series of propofol analogs
correlate with potency for potentiation of gamma-aminobutyric acid (GABA)
current at the GABA(A) receptor but not with lipid solubility. Evidence for a common binding cavity for three general anesthetics
within the GABAA receptor.Jenkins A, Greenblatt EP, Faulkner HJ,
Bertaccini E, Light A, Lin A, Andreasen A, Viner A, Trudell JR, Harrison
NL. Arg-274 and Leu-277 of the gamma-aminobutyric acid type A receptor
alpha 2 subunit define agonist efficacy and potency. Propofol increases agonist efficacy at the GABA(A) receptor. The actions of ether, alcohol and alkane general anaesthetics on
GABAA and glycine receptors and the effects of TM2 and TM3 mutations. Agonist gating and isoflurane potentiation in the human gamma-aminobutyric
acid type A receptor determined by the volume of a second transmembrane
domain residue. Propofol and other intravenous anesthetics have sites of action on
the gamma-aminobutyric acid type A receptor distinct from that for
isoflurane. Neurosteroids act on the GABA(A) receptor at sites on the N-terminal
side of the middle of TM2. Trichloroethanol modulation of recombinant GABAA, glycine and GABA
rho 1 receptors. A deficit of functional GABA(A) receptors in neurons of beta 3
subunit knockout mice. Sites of alcohol and volatile anaesthetic action on GABA(A) and
glycine receptors. Alpha subunit isoform influences GABA(A) receptor modulation by
propofol. Neuropharmacology. Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have
epilepsy, cleft palate, and hypersensitive behavior. A single point mutation in the pore region of the epithelial Na+ channel
changes ion selectivity by modifying molecular sieving. On the molecular basis of ion permeation in the epithelial Na+ channel. Kinetic Analysis of Block of Open Sodium Channels by a Peptide Containing
the Isoleucine, Phenylalanine, and Methionine (IFM) Motif from the
Inactivation Gate Tetracaine Reports a Conformational Change in the Pore of Cyclic
Nucleotide-gated Channels Gating and Conduction Properties of a Sodium-activated Cation Channel from
Lobster Olfactory Receptor Neurons A.B. Zhainazarov, B.W. Ache Interdomain Interactions Underlying Activation of Cyclic Nucleotide-Gated
Channels. Mechanism of tetracaine block of cyclic nucleotide-gated channels. Mechanism of action of K channel openers on skeletal muscle KATP
channels. Subunit interactions in the activation of cyclic nucleotide-gated ion
channels. Modification by protons of frog skeletal muscle KATP channels : Effects on
ion conduction and nucleotide inhibition. Molecular mechanism for ligand discrimination of cyclic nucleotide-gated
channels. Intracellular protons control the affinity of skeletal muscle
ATP-sensitive K+ channels for potassium-channel-openers. |
Contact us -
Legal notice - Chinese reg.num.(京ICP备06015605号) - Last modified:
4-feb-11
- ©2004-11 Bio-Logic SAS -
|